Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485264 | 1.00 | HRH3 (0.36) | HRH3SLC6A4SCN7AKCNH2KDM4E | |
| SCHEMBL7489272 | 0.98 | SLC6A4 (0.38) | HRH3SLC6A4SCN7AKCNH2KDM4E | |
| SCHEMBL7490226 | 0.94 | SLC6A4 (0.35) | HRH3SLC6A4SCN7AKCNH2HCRTR1 | |
| SCHEMBL7490219 | 0.94 | SLC6A4 (0.35) | HRH3SLC6A4SCN7AKCNH2HCRTR1 | |
| SCHEMBL7485497 | 0.93 | HRH3 (0.35) | HRH3SLC6A4SCN7AKCNH2ALDH1A1 | |
| SCHEMBL7493801 | 0.93 | HRH3 (0.35) | HRH3SLC6A4SCN7AKCNH2ALDH1A1 | |
| SCHEMBL7485506 | 0.93 | HRH3 (0.35) | HRH3SLC6A4SCN7AKCNH2ALDH1A1 | |
| SCHEMBL7490187 | 0.92 | SLC6A4 (0.37) | HRH3SLC6A4SCN7AKCNH2KDM4E | |
| SCHEMBL7490184 | 0.92 | SLC6A4 (0.37) | HRH3SLC6A4SCN7AKCNH2KDM4E | |
| SCHEMBL7496940 | 0.91 | SLC6A4 (0.38) | HRH3SLC6A4SCN7AKCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |