Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663230 | 0.93 | TDP1 (0.48) | SMN1; SMN2TDP1GAAPKMHTT | |
| Fluoride SCHEMBL7484762 | 0.83 | TDP1 (0.44) | SMN1; SMN2TDP1HTTMEN1KMT2A | |
| Fluoride SCHEMBL7478380 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2TDP1GAAPKMHTT | |
| SCHEMBL6596781 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2TDP1GAAPKMHTT | |
| SCHEMBL6006476 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2TDP1GAAPKMHTT | |
| Fluoride SCHEMBL7489306 | 0.77 | KMT2A (0.40) | SMN1; SMN2TDP1HTTMEN1KMT2A | |
| SCHEMBL1128585 | 0.76 | GAA (0.66) | SMN1; SMN2TDP1GAAPKMHTT | |
| SCHEMBL1516437 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2PKMHTTMEN1KMT2A | |
| SCHEMBL16448135 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2TDP1MEN1KMT2AHPGD | |
| SCHEMBL6955711 | 0.74 | TDP1 (0.50) | SMN1; SMN2TDP1PKMHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933364-B1 | Imidazolate sulfur difluorides | AIR PROD & CHEM (US) | 2002-05-02 | — | — | EP | disclosed |
| US-5939546-A | USEFUL DEOXOFLUORINATION REAGENTS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1999-08-17 | — | — | US | disclosed |
| EP-0933364-A1 | Imidazolate sulfur difluorides | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1999-08-04 | — | — | EP | disclosed |