Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 17/20 | 0.55 |
| ▸ | PPARA | Q07869 | 14/20 | 0.55 |
| ▸ | PPARD | Q03181 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123237 | 0.86 | PPARG (0.73) | PPARGPPARAPPARD | |
| SCHEMBL12469332 | 0.83 | MEN1 (0.54) | FFAR1KDM4EMEN1KMT2APPARG | |
| SCHEMBL3278854 | 0.82 | MAPT (0.68) | FFAR1PPARGPPARA | |
| SCHEMBL4036791 | 0.81 | PPARG (0.67) | PPARGPPARA | |
| SCHEMBL31180905 | 0.81 | MAPT (0.53) | FFAR1KDM4EMEN1KMT2APPARG | |
| SCHEMBL6387594 | 0.81 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL4031706 | 0.81 | KDR (0.57) | FFAR1KDM4EPPARGPPARAPPARD | |
| SCHEMBL12469625 | 0.81 | MEN1 (0.54) | KDM4EMEN1KMT2APPARGPPARA | |
| SCHEMBL7486859 | 0.80 | KDM4E (0.57) | FFAR1KDM4EPPARGPPARAPPARD | |
| SCHEMBL15325997 | 0.80 | MEN1 (0.58) | KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643050-B1 | Oxazolidinedione derivatives and their use as hypoglycemic agent | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-5614544-A | HYPOGLYCEMIC AND HYPOLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0643050-A1 | Oxazolidinedione derivatives and their use as hypoglycemic agent | Takeda Chemical Industries, Ltd. (JP) | 1995-03-15 | — | — | EP | disclosed |