SCHEMBL7486192

SCHEMBL7486192

CNc1nc2c(OC(F)(F)F)cccc2c2c1CCN2c1ccccc1C

nearest known ligand 0.78

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.52
ALDH1A1 P00352 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7495928 0.90 KDM4E (0.45) KDM4EALDH1A1
SCHEMBL7486433 0.88 KDM4E (0.43) KDM4EALDH1A1
SCHEMBL7484334 0.88 KDM4E (0.49) KDM4EALDH1A1
SCHEMBL7496554 0.87 KDM4E (0.47) KDM4EALDH1A1
SCHEMBL7484498 0.87 KDM4E (0.54) KDM4EALDH1A1
SCHEMBL7490165 0.86 KDM4E (0.46) KDM4EALDH1A1
SCHEMBL8073493 0.86 KDM4E (0.46) KDM4EALDH1A1
SCHEMBL30862858 0.85 KDM4E (0.62) KDM4EALDH1A1
SCHEMBL29493309 0.85 KDM4E (0.62) KDM4EALDH1A1
SCHEMBL9685793 0.85 KDM4E (0.62) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0966466-B1 PYRROLO 3,2-c]QUINOLINE DERIVATIVES CONTAINING HALOALKOXY GROUP AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF KOREA RES INST CHEM TECH (KR) 2002-07-03 EP disclosed
US-6011044-A ANTIULCER AGENTS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2000-01-04 US disclosed