Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.43 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.42 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.42 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611278 | 0.96 | GRIK1 (0.47) | GRIK1GRIK2GRIK3GRIA1GRIA2 | |
| SCHEMBL8609140 | 0.86 | GRIA1 (0.50) | GRIK1GRIK2GRIK3GRIA1GRIA2 | |
| SCHEMBL8609144 | 0.86 | GRIA1 (0.50) | GRIK1GRIK2GRIK3GRIA1GRIA2 | |
| SCHEMBL8611525 | 0.84 | GRIK1 (0.57) | GRIK1GRIK2GRIK3GRIA1GRIA2 | |
| SCHEMBL8674016 | 0.81 | GRIA1 (0.64) | GRIK1GRIK2GRIK3GRIA1GRIA2 | |
| SCHEMBL7665623 | 0.81 | GRIA1 (0.66) | GRIK1GRIK2GRIK3GRIA1GRIA2 | |
| SCHEMBL8610117 | 0.81 | GRIK1 (0.46) | GRIK1GRIK2GRIK3GRIA1GRIA2 | |
| SCHEMBL8611345 | 0.80 | GRIK1 (0.57) | GRIK1GRIK2GRIK3GRIA1GRIA2 | |
| SCHEMBL8609423 | 0.78 | GRIA1 (0.65) | GRIK1GRIK2GRIK3GRIA1GRIA2 | |
| SCHEMBL8672407 | 0.76 | GRIK1 (0.69) | GRIK1GRIK2GRIK3GRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799224-B1 | QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AG (DE) | 2002-04-17 | — | — | EP | disclosed |
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5849743-A | Quinoxalines and drugs prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| WO-1996019476-A1 | NOVEL QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-27 | — | — | WO | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |