Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | CCR9 | P51686 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487037 | 1.00 | SLC6A4 (0.33) | SLC6A4KDM2BHRH3HCRTR1HCRTR2 | |
| SCHEMBL7490748 | 0.91 | KDM2B (0.33) | SLC6A4KDM2BHRH3SCN7AKCNH2 | |
| SCHEMBL7490741 | 0.91 | KDM2B (0.33) | SLC6A4KDM2BHRH3SCN7AKCNH2 | |
| SCHEMBL7491090 | 0.88 | HRH3 (0.36) | SLC6A4KDM2BHRH3HCRTR1HCRTR2 | |
| SCHEMBL7487436 | 0.86 | SCN7A (0.35) | SLC6A4KDM2BHRH3SCN7AKCNH2 | |
| SCHEMBL7491380 | 0.85 | DPP4 (0.40) | SLC6A4HRH3KCNH2 | |
| SCHEMBL7491397 | 0.85 | DPP4 (0.40) | SLC6A4HRH3KCNH2 | |
| SCHEMBL7491392 | 0.84 | SLC6A4 (0.42) | SLC6A4HRH3HCRTR1HCRTR2SCN7A | |
| SCHEMBL7496188 | 0.84 | DPP4 (0.35) | SLC6A4HRH3HCRTR1HCRTR2SCN7A | |
| SCHEMBL7496176 | 0.84 | DPP4 (0.35) | SLC6A4HRH3HCRTR1HCRTR2SCN7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |