SCHEMBL7487076

SCHEMBL7487076

CCCCCCC(C)N1C(=O)C2CC2C1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP2C19 P33261 1/20 0.37
GBA1 P04062 1/20 0.36
PKM P14618 1/20 0.36
HTT P42858 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CCR2 P41597 1/20 0.35
PRKCD Q05655 4/20 0.34
SHMT2 P34897 1/20 0.34
ADH1B P00325 1/20 0.33
ADH1C P00326 1/20 0.33
ADH1A P07327 1/20 0.33
ADH4 P08319 1/20 0.33
ADH7 P40394 1/20 0.33
ACE P12821 2/20 0.33
PTPN1 P18031 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28885887 0.80 MEN1 (0.49) SMN1; SMN2LMNAALDH1A1CYP2C19HTT
SCHEMBL28369411 0.80 MEN1 (0.49) SMN1; SMN2LMNAALDH1A1CYP2C19HTT
SCHEMBL28369781 0.80 MEN1 (0.49) SMN1; SMN2LMNAALDH1A1CYP2C19HTT
SCHEMBL28369220 0.80 MEN1 (0.49) SMN1; SMN2LMNAALDH1A1CYP2C19HTT
SCHEMBL28369237 0.80 MEN1 (0.49) SMN1; SMN2LMNAALDH1A1CYP2C19HTT
SCHEMBL28372885 0.80 MEN1 (0.49) SMN1; SMN2LMNAALDH1A1CYP2C19HTT
SCHEMBL28369413 0.80 MEN1 (0.49) SMN1; SMN2LMNAALDH1A1CYP2C19HTT
SCHEMBL28373245 0.80 MEN1 (0.49) SMN1; SMN2LMNAALDH1A1CYP2C19HTT
SCHEMBL28369832 0.80 MEN1 (0.49) SMN1; SMN2LMNAALDH1A1CYP2C19HTT
SCHEMBL28375155 0.78 MEN1 (0.50) SMN1; SMN2LMNAALDH1A1CYP2C19HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0929522-B1 INSECT-REPELLENT FORMULATIONS PFIZER LTD (GB) 2002-12-18 EP disclosed
US-6130241-A Insect-repellent formulations PFIZER INC. (US) 2000-10-10 US disclosed
EP-0929522-A1 INSECT-REPELLENT FORMULATIONS Pfizer Limited (GB) 1999-07-21 EP disclosed
WO-1998013345-A1 INSECT-REPELLENT FORMULATIONS PFIZER LIMITED (GB) 1998-04-02 WO disclosed