Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484427 | 0.94 | KDR (1.00) | KDRPDGFRA | |
| SCHEMBL27081475 | 0.92 | PDGFRA (0.95) | KDRPDGFRA | |
| SCHEMBL29973354 | 0.92 | PDGFRA (0.95) | KDRPDGFRA | |
| SCHEMBL7481397 | 0.91 | PDGFRA (1.00) | KDRPDGFRA | |
| SCHEMBL3931065 | 0.90 | PDGFRA (1.00) | KDRPDGFRA | |
| SCHEMBL1877834 | 0.89 | KDR (0.92) | KDRPDGFRA | |
| SCHEMBL7482526 | 0.89 | PDGFRA (0.89) | KDRPDGFRA | |
| SCHEMBL7485558 | 0.88 | KDR (1.00) | KDRPDGFRA | |
| SCHEMBL7486940 | 0.88 | PDGFRA (0.83) | KDRPDGFRA | |
| SCHEMBL7489320 | 0.88 | PDGFRA (0.87) | KDRPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860433-B1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KIRIN BREWERY (JP) | 2002-07-03 | — | — | EP | claimed |
| US-6143764-A | ETHER DERIVATIVES OF QUINOLINE, ANTITUMOR AGENTS | KIRIN BEER KABUSHIKI KAISHA (JP) | 2000-11-07 | — | — | US | claimed |
| EP-0860433-B1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KIRIN BREWERY (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-6143764-A | ETHER DERIVATIVES OF QUINOLINE, ANTITUMOR AGENTS | KIRIN BEER KABUSHIKI KAISHA (JP) | 2000-11-07 | — | — | US | disclosed |