Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 18/20 | 0.74 |
| ▸ | KDR | P35968 | 17/20 | 0.74 |
| ▸ | AXL | P30530 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3936662 | 0.92 | KDR (0.74) | PDGFRAKDR | |
| SCHEMBL5091900 | 0.91 | PDGFRA (0.72) | PDGFRAKDRAXL | |
| SCHEMBL4475483 | 0.91 | PDGFRA (0.72) | PDGFRAKDR | |
| SCHEMBL7488292 | 0.90 | PDGFRA (0.71) | PDGFRAKDR | |
| SCHEMBL6227724 | 0.90 | PDGFRA (0.71) | PDGFRAKDR | |
| SCHEMBL6227624 | 0.90 | PDGFRA (0.77) | PDGFRAKDR | |
| SCHEMBL1878994 | 0.90 | PDGFRA (0.77) | PDGFRAKDRAXL | |
| SCHEMBL4465899 | 0.89 | PDGFRA (0.70) | PDGFRAKDR | |
| SCHEMBL5092913 | 0.89 | PDGFRA (0.70) | PDGFRAKDR | |
| SCHEMBL7476738 | 0.89 | PDGFRA (0.75) | PDGFRAKDRAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860433-B1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KIRIN BREWERY (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-6143764-A | ETHER DERIVATIVES OF QUINOLINE, ANTITUMOR AGENTS | KIRIN BEER KABUSHIKI KAISHA (JP) | 2000-11-07 | — | — | US | disclosed |