Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 7/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498821 | 0.98 | PTGIR (0.64) | PTGIRSIGMAR1NR4A2RXRARXRB | |
| SCHEMBL7488572 | 0.98 | PTGIR (0.64) | PTGIRSIGMAR1NR4A2RXRARXRB | |
| SCHEMBL7493431 | 0.98 | PTGIR (0.64) | PTGIRSIGMAR1NR4A2RXRARXRB | |
| SCHEMBL7487288 | 0.98 | PTGIR (0.64) | PTGIRSIGMAR1NR4A2RXRARXRB | |
| SCHEMBL7490686 | 0.96 | PTGIR (0.60) | PTGIRSIGMAR1NR4A2RXRARXRB | |
| SCHEMBL7488099 | 0.93 | PTGIR (0.59) | PTGIRSIGMAR1 | |
| SCHEMBL7483903 | 0.87 | PTGIR (0.51) | PTGIRSIGMAR1NR4A2RXRARXRB | |
| SCHEMBL7487040 | 0.86 | PTGIR (0.52) | PTGIRNR4A2RXRARXRBRXRG | |
| SCHEMBL7490579 | 0.85 | PTGIR (0.47) | PTGIRNR4A2RXRARXRBRXRG | |
| SCHEMBL7494714 | 0.84 | PTGIR (0.72) | PTGIRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842161-B1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-09-18 | — | — | EP | disclosed |
| EP-1213285-A2 | 4,5-dipheny-oxazole derivatives and their use as platelet aggregation inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6300344-B1 | FOR THERAPEUTIC AND/OR PROPHYLACTIC TREATMENT OF ARTERIAL OBSTRUCTION, CEREBROVASCULAR DISEASE, HEPATIC CIRRHOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASE, RESTENOSIS AFTER PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY, HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| US-5972965-A | USEFUL FOR INHIBITION OF PLATELET AGGREGATION, VASODILATION, ANTIHYPERTENSIVE ACTIVITY AND PROSTAGLANDIN AGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0842161-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997003973-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-06 | — | — | WO | disclosed |