Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485138 | 0.94 | HRH3 (0.41) | HRH3SCN7AKCNH2SLC6A4HCRTR1 | |
| SCHEMBL7491090 | 0.93 | HRH3 (0.36) | HRH3SCN7AKCNH2SLC6A4HCRTR1 | |
| SCHEMBL7487436 | 0.90 | SCN7A (0.35) | HRH3SCN7AKCNH2SLC6A4ROCK2 | |
| SCHEMBL7490886 | 0.89 | HRH3 (0.39) | HRH3SLC6A4HCRTR1HCRTR2KDM2B | |
| SCHEMBL7490219 | 0.86 | SLC6A4 (0.35) | HRH3SCN7AKCNH2SLC6A4HCRTR1 | |
| SCHEMBL7490226 | 0.86 | SLC6A4 (0.35) | HRH3SCN7AKCNH2SLC6A4HCRTR1 | |
| SCHEMBL7491433 | 0.86 | HRH3 (0.36) | HRH3SCN7AKCNH2SLC6A4HCRTR1 | |
| SCHEMBL7951419 | 0.86 | HRH3 (0.36) | HRH3SCN7AKCNH2SLC6A4HCRTR1 | |
| SCHEMBL7495707 | 0.85 | SLC6A4 (0.35) | HRH3SCN7AKCNH2SLC6A4HCRTR1 | |
| SCHEMBL7958242 | 0.85 | SLC6A4 (0.35) | HRH3SCN7AKCNH2SLC6A4HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |