Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 11/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485288 | 0.85 | P2RY2 (0.38) | P2RY2RPS6KA5GAA | |
| SCHEMBL7496798 | 0.80 | P2RY2 (0.35) | P2RY2GAA | |
| SCHEMBL7493681 | 0.80 | P2RY2 (0.43) | P2RY2 | |
| SCHEMBL7491790 | 0.79 | P2RY2 (0.47) | P2RY2 | |
| SCHEMBL7487100 | 0.79 | P2RY2 (0.34) | P2RY2GAA | |
| SCHEMBL7492901 | 0.78 | P2RY2 (0.37) | P2RY2 | |
| SCHEMBL7488365 | 0.76 | P2RY2 (0.34) | P2RY2 | |
| SCHEMBL7509963 | 0.73 | P2RY2 (0.32) | P2RY2 | |
| SCHEMBL7486664 | 0.70 | P2RY2 (0.50) | P2RY2 | |
| SCHEMBL7488855 | 0.70 | P2RY2 (0.49) | P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996617-B1 | 2,4-Dithi(oxo)-pyridin-5-yl compounds bearing a tricyclic substituent useful as P2 purinoceptor antagonists | ASTRAZENECA AB (SE) | 2002-01-09 | — | — | EP | disclosed |