Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488143 | 1.00 | DPP4 (0.38) | DPP4SCN7AKCNH2PREPHRH3 | |
| SCHEMBL7497266 | 0.92 | DPP4 (0.39) | DPP4SCN7AKCNH2PREPHRH3 | |
| SCHEMBL7452050 | 0.92 | DPP4 (0.39) | DPP4SCN7AKCNH2PREPHRH3 | |
| SCHEMBL7493582 | 0.92 | DPP4 (0.38) | DPP4SCN7AKCNH2PREPHRH3 | |
| SCHEMBL7493573 | 0.92 | DPP4 (0.38) | DPP4SCN7AKCNH2PREPHRH3 | |
| SCHEMBL7491433 | 0.89 | HRH3 (0.36) | DPP4SCN7AKCNH2PREPHRH3 | |
| SCHEMBL7491090 | 0.89 | HRH3 (0.36) | DPP4SCN7AKCNH2PREPHRH3 | |
| SCHEMBL7951419 | 0.89 | HRH3 (0.36) | DPP4SCN7AKCNH2PREPHRH3 | |
| SCHEMBL7493319 | 0.89 | DPP4 (0.36) | DPP4SCN7AKCNH2PREPHRH3 | |
| SCHEMBL7493329 | 0.89 | DPP4 (0.36) | DPP4SCN7AKCNH2PREPHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |