Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.31 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.31 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL389574 | 0.88 | SLC7A5 (0.41) | SLC7A5GRIK1GRIA2GRIA4GRIK3 | |
| Alanine SCHEMBL5224821 | 0.88 | SLC7A5 (0.40) | SLC7A5LTA4HSLC1A3SLC1A2SLC1A1 | |
| Alanine SCHEMBL4052793 | 0.88 | SLC7A5 (0.40) | SLC7A5LTA4HSLC1A3SLC1A2SLC1A1 | |
| Alanine SCHEMBL1577981 | 0.88 | SLC7A5 (0.41) | SLC7A5GRIK1GRIA2GRIA4GRIK3 | |
| D-Alanine SCHEMBL9174821 | 0.88 | SLC7A5 (0.40) | SLC7A5LTA4HSLC1A3SLC1A2SLC1A1 | |
| Alanine SCHEMBL9653878 | 0.86 | SLC7A5 (0.39) | SLC7A5GRIK1GRIA2GRIA4GRIK3 | |
| Benzene SCHEMBL27737074 | 0.76 | — | — | |
| Thiophene SCHEMBL28738281 | 0.74 | TP53 (0.38) | SLC7A5 | |
| Pyrrole SCHEMBL28150602 | 0.74 | TDP1 (0.43) | — | |
| Valine SCHEMBL111113 | 0.74 | SLC7A5 (0.65) | SLC7A5GRIK1GRIA2GRIA4GRIK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219603-A2 | Tryptophan analogs in proteins, peptides and peptidic structures | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2002-07-03 | — | — | EP | disclosed |