Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489205 | 1.00 | HRH3 (0.42) | HRH3KCNH2PREPMEN1RAB9A | |
| SCHEMBL7444342 | 0.94 | HRH3 (0.50) | HRH3KCNH2 | |
| SCHEMBL7444329 | 0.94 | HRH3 (0.50) | HRH3KCNH2 | |
| SCHEMBL7488638 | 0.85 | HRH3 (0.36) | HRH3MEN1RAB9AKMT2ASLC6A4 | |
| SCHEMBL7488647 | 0.85 | HRH3 (0.36) | HRH3MEN1RAB9AKMT2ASLC6A4 | |
| SCHEMBL7484052 | 0.85 | F10 (0.41) | HRH3PREPMEN1RAB9AKMT2A | |
| SCHEMBL7488272 | 0.85 | HRH3 (0.43) | HRH3KCNH2SLC6A4 | |
| SCHEMBL7488283 | 0.85 | HRH3 (0.43) | HRH3KCNH2SLC6A4 | |
| SCHEMBL7491320 | 0.83 | HRH3 (0.46) | HRH3KCNH2PREP | |
| SCHEMBL7485506 | 0.82 | HRH3 (0.35) | HRH3KCNH2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |