Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7483507 | 0.95 | CYP4F2 (0.46) | CYP4F2CYP4A11POLBNPC1RAB9A | |
| SCHEMBL6100697 | 0.95 | CYP4F2 (0.46) | CYP4F2CYP4A11POLBNPC1RAB9A | |
| SCHEMBL6100693 | 0.95 | CYP4F2 (0.46) | CYP4F2CYP4A11POLBNPC1RAB9A | |
| SCHEMBL1519271 | 0.84 | CYP4F2 (0.50) | CYP4F2CYP4A11POLBNPC1RAB9A | |
| SCHEMBL1519097 | 0.82 | POLB (0.58) | CYP4F2CYP4A11POLBNPC1ALDH1A1 | |
| SCHEMBL1519167 | 0.82 | CYP4F2 (0.48) | CYP4F2CYP4A11POLBNPC1ALDH1A1 | |
| SCHEMBL11465271 | 0.81 | CYP4F2 (0.49) | CYP4F2CYP4A11POLBNPC1RAB9A | |
| SCHEMBL7203233 | 0.81 | CYP4F2 (0.47) | CYP4F2CYP4A11POLBNPC1RAB9A | |
| SCHEMBL7485154 | 0.80 | MAPT (0.48) | POLBNPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL7485148 | 0.80 | MAPT (0.48) | POLBNPC1RAB9AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825189-B1 | 1,4-BENZODIOXIN DERIVATIVES | NISSHIN PHARMA INC (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-6130243-A | PROPHYLACTIC OR THERAPEUTIC AGENT FOR DIABETES, HYPERGLYCEMIA AND OBESITY IN MAMMALS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-0825189-A1 | 1,4-BENZODIOXIN DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |