Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490251 | 1.00 | POLB (0.41) | POLBFFAR1OGATP53RAB9A | |
| SCHEMBL7492119 | 0.92 | POLB (0.45) | POLBFFAR1OGATP53RAB9A | |
| SCHEMBL7484692 | 0.92 | POLB (0.45) | POLBFFAR1OGATP53RAB9A | |
| SCHEMBL7484687 | 0.92 | POLB (0.45) | POLBFFAR1OGATP53RAB9A | |
| SCHEMBL7491239 | 0.92 | POLB (0.45) | POLBFFAR1OGATP53RAB9A | |
| SCHEMBL7491235 | 0.92 | POLB (0.45) | POLBFFAR1OGATP53RAB9A | |
| SCHEMBL7492124 | 0.92 | POLB (0.45) | POLBFFAR1OGATP53RAB9A | |
| SCHEMBL7487732 | 0.88 | POLB (0.42) | POLBFFAR1OGATP53RAB9A | |
| SCHEMBL7487735 | 0.88 | POLB (0.42) | POLBFFAR1OGATP53RAB9A | |
| SCHEMBL7483004 | 0.87 | MAPT (0.46) | POLBTP53RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989114-B1 | N,N-DISUBSTITUTED AMIC ACID DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2002-07-24 | — | — | EP | disclosed |
| EP-0989114-A1 | N,N-DISUBSTITUTED AMIC ACID DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-03-29 | — | — | EP | disclosed |
| US-5981573-A | INHIBIT PROTEIN-FARNESYL TRANSFERASE (PFT) IN VIVO THEREBY SUPPRESSING FUNCTION OF ONCOGENE PROTEIN RAS AND THUS PRESENTING ANTITUMOR ACTIVITIES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |