Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487193 | 1.00 | PTGIR (0.72) | PTGIRPOLBCD274PTGER4PTGER3 | |
| SCHEMBL8549446 | 0.92 | PTGIR (0.64) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL8546649 | 0.92 | PTGIR (0.64) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL7490346 | 0.91 | PTGIR (0.75) | PTGIRPOLBCD274PTGER4PTGER3 | |
| SCHEMBL7487199 | 0.91 | PTGIR (0.75) | PTGIRPOLBCD274PTGER4PTGER3 | |
| SCHEMBL6611962 | 0.86 | PTGIR (0.86) | PTGIRPOLBCD274PTGER4PTGER3 | |
| SCHEMBL7483613 | 0.86 | PTGIR (0.86) | PTGIRPOLBCD274PTGER4PTGER3 | |
| SCHEMBL7485700 | 0.84 | PTGIR (0.69) | PTGIRCD274KDM4EALDH1A1 | |
| SCHEMBL7487768 | 0.84 | PTGIR (1.00) | PTGIRPOLBCD274PTGER4PTGER3 | |
| SCHEMBL7488410 | 0.84 | PTGIR (1.00) | PTGIRPOLBCD274PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842161-B1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-09-18 | — | — | EP | claimed |