Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.55 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22417702 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1RAB9ANPC1TDP1 | |
| SCHEMBL16899020 | 0.83 | XIAP (0.59) | XIAPBIRC2SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL431114 | 0.83 | XIAP (0.55) | XIAPBIRC2SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL28734996 | 0.80 | XIAP (0.56) | XIAPBIRC2SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL7727310 | 0.79 | XIAP (0.55) | XIAPBIRC2SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL432255 | 0.79 | XIAP (0.51) | XIAPBIRC2SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL4138786 | 0.79 | XIAP (0.51) | XIAPBIRC2SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL4377108 | 0.78 | XIAP (0.62) | XIAPBIRC2SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL13403439 | 0.78 | XIAP (0.62) | XIAPBIRC2SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL29751774 | 0.77 | XIAP (0.65) | XIAPBIRC2SMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250324-A1 | BIARYL COMPOUNDS, THEIR PREPARATION AND THEIR USE IN THERAPY | RiboTargets Limited (GB) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001055111-A1 | BIARYL COMPOUNDS, THEIR PREPARATION AND THEIR USE IN THERAPY | RIBOTARGETS LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |