Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 9/20 | 0.40 |
| ▸ | CNR2 | P34972 | 9/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330679 | 0.89 | GRIN2B (0.42) | KMT2ADRD4MEN1LMNACYP1A2 | |
| SCHEMBL7494625 | 0.85 | CCR3 (0.42) | CCR3CNR1CNR2KMT2ANPC1 | |
| SCHEMBL7497394 | 0.85 | DRD4 (0.42) | KMT2ADRD4MEN1LMNACYP1A2 | |
| SCHEMBL7490791 | 0.81 | KMT2A (0.48) | CCR3CNR1CNR2KMT2ANPC1 | |
| SCHEMBL7499277 | 0.74 | MEN1 (0.54) | CCR3KMT2ADRD4MEN1LMNA | |
| SCHEMBL7499283 | 0.74 | MEN1 (0.54) | CCR3KMT2ADRD4MEN1LMNA | |
| SCHEMBL7495888 | 0.74 | DRD4 (0.41) | CCR3CNR2KMT2ADRD4MEN1 | |
| SCHEMBL12610669 | 0.72 | NPC1 (0.53) | CCR3CNR1CNR2KMT2ANPC1 | |
| SCHEMBL7496846 | 0.71 | DRD4 (0.48) | CNR2DRD4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7494865 | 0.70 | MEN1 (0.49) | CCR3KMT2ADRD4MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760362-B1 | DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN SEIFUN GROUP INC (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |