Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 4/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577288 | 0.92 | GBA1 (0.46) | GSK3BCTSDGBA1 | |
| SCHEMBL575811 | 0.88 | GBA1 (0.46) | GSK3BCTSDGBA1 | |
| SCHEMBL10338620 | 0.88 | CXCR4 (0.32) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL577179 | 0.86 | GBA1 (0.47) | GSK3BCTSDGBA1 | |
| SCHEMBL10374632 | 0.86 | MLNR (0.42) | KMT2ACTSDGAA | |
| SCHEMBL576797 | 0.86 | GBA1 (0.50) | GSK3BCTSDGBA1 | |
| SCHEMBL577564 | 0.86 | GBA1 (0.50) | GSK3BCTSDGBA1 | |
| SCHEMBL577053 | 0.86 | GBA1 (0.50) | GSK3BCTSDGBA1 | |
| SCHEMBL9098473 | 0.84 | PSEN1 (0.41) | HRH3GAA | |
| SCHEMBL10433082 | 0.81 | KCNJ1 (0.47) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223166-A1 | Linked cyclic polyamines with activity against hiv. | AnorMED Inc. (CA) | 2002-07-17 | — | — | EP | disclosed |
| EP-0619813-A1 | LINKED CYCLIC POLYAMINES WITH ACTIVITY AGAINST HIV | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1994-10-19 | — | — | EP | disclosed |
| WO-1993012096-A1 | LINKED CYCLIC POLYAMINES WITH ACTIVITY AGAINST HIV | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1993-06-24 | — | — | WO | disclosed |