Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 7/20 | 0.34 |
| ▸ | FNTB | P49356 | 7/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7483971 | 0.83 | FNTA (0.47) | FNTAFNTBCYP19A1 | |
| Hydrochloric Acid SCHEMBL7482278 | 0.82 | FNTA (0.47) | FNTAFNTBCYP19A1 | |
| SCHEMBL7480201 | 0.81 | MAPK14 (0.46) | MGLLKCNH2FNTAFNTBCYP19A1 | |
| SCHEMBL7483881 | 0.81 | FNTA (0.38) | SLC6A2SLC6A4PARP1FNTAFNTB | |
| Hydrochloric Acid SCHEMBL7748868 | 0.81 | FNTA (0.38) | SLC6A2SLC6A4PARP1FNTAFNTB | |
| SCHEMBL7480437 | 0.81 | CHRM2 (0.38) | FNTAFNTBABCG2 | |
| SCHEMBL7156162 | 0.79 | CYP19A1 (0.42) | CYP19A1CPA1 | |
| SCHEMBL7584664 | 0.79 | FNTA (0.38) | SLC6A2SLC6A4FNTAFNTBCYP19A1 | |
| SCHEMBL7482744 | 0.79 | FNTA (0.41) | HCRTR1HCRTR2SLC6A2SLC6A4FNTA | |
| Hydrochloric Acid SCHEMBL7750453 | 0.78 | FNTA (0.38) | SLC6A2SLC6A4FNTAFNTBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002538121-A | — | — | 2002-11-12 | — | — | JP | claimed |
| EP-1165084-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASES | MERCK & CO INC (US) | 2002-05-15 | — | — | EP | claimed |
| EP-1165084-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASES | Merck & Co., Inc. (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2001022963-A1 | METHOD OF PREVENTING OSTEOPOROSIS | MERCK & CO., INC. (US) | 2001-04-05 | — | — | WO | claimed |
| WO-2000051614-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASES | MERCK & CO., INC. (US) | 2000-09-08 | — | — | WO | claimed |
| EP-1165084-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASES | MERCK & CO INC (US) | 2002-05-15 | — | — | EP | disclosed |
| EP-1165084-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASES | Merck & Co., Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2001022963-A1 | METHOD OF PREVENTING OSTEOPOROSIS | MERCK & CO., INC. (US) | 2001-04-05 | — | — | WO | disclosed |
| WO-2000051614-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASES | MERCK & CO., INC. (US) | 2000-09-08 | — | — | WO | disclosed |