Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5826943 | 0.99 | NPY1R (0.38) | NPY1RKDM4ECHRM1GRIN2BLMNA | |
| Hydrochloric Acid SCHEMBL5826984 | 0.89 | NPY1R (0.39) | NPY1RKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL6496723 | 0.88 | NPY1R (0.38) | NPY1RMEN1KMT2A | |
| SCHEMBL5826785 | 0.88 | NPY1R (0.38) | NPY1RALDH1A1HPGDMAPTPI4KB | |
| Hydrochloric Acid SCHEMBL6209582 | 0.87 | MAPT (0.41) | NPY1RKDM4ECHRM1GRIN2BLMNA | |
| SCHEMBL5826461 | 0.86 | NPY1R (0.50) | NPY1RLMNAMAPT | |
| SCHEMBL5826672 | 0.86 | SLC2A1 (0.40) | NPY1RKDM4ELMNASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL5828250 | 0.83 | NPY1R (0.40) | NPY1RLMNAMAPT | |
| Hydrochloric Acid SCHEMBL5827007 | 0.83 | NPY1R (0.42) | NPY1RKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL5826603 | 0.83 | NPY1R (0.39) | NPY1RKDM4ELMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238979-A1 | FUSED HETEROTRICYCLIC COMPOUNDS, PROCESS FOR PREPARING THE COMPOUNDS AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-09-11 | — | — | EP | disclosed |