SCHEMBL7492912

SCHEMBL7492912

CCN1CCNCCN(Cc2nccn2C)CC1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 7/20 0.41
EGLN3 Q9H6Z9 1/20 0.41
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TLR7 Q9NYK1 1/20 0.38
AURKA O14965 2/20 0.38
MAPKAPK2 P49137 1/20 0.38
PIM1 P11309 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HIF1A Q16665 1/20 0.36
DCPS Q96C86 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7613456 0.94 EGLN1 (0.44) EGLN1EGLN3ALDH1A1POLBNPSR1
SCHEMBL209630 0.92 EGLN1 (0.44) EGLN1EGLN3ALDH1A1POLBNPSR1
SCHEMBL7462242 0.91 EGLN1 (0.44) EGLN1EGLN3ALDH1A1POLBNPSR1
SCHEMBL20328914 0.91 EGLN1 (0.44) EGLN1EGLN3ALDH1A1POLBNPSR1
SCHEMBL1332937 0.91 EGLN1 (0.44) EGLN1EGLN3ALDH1A1POLBNPSR1
SCHEMBL17996825 0.84 EGLN1 (0.48) EGLN1EGLN3ALDH1A1POLBNPSR1
SCHEMBL17305900 0.84 EGLN1 (0.48) EGLN1EGLN3ALDH1A1POLBNPSR1
SCHEMBL1331195 0.79 EGLN1 (0.45) EGLN1EGLN3ALDH1A1POLBNPSR1
SCHEMBL17888434 0.79 EGLN1 (0.45) EGLN1EGLN3ALDH1A1POLBNPSR1
SCHEMBL825405 0.79 MAPKAPK2 (0.33) TLR7MAPKAPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1208186-A1 COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE UNILEVER PLC (GB) 2002-05-29 EP disclosed
WO-2001016270-A1 COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE UNILEVER PLC (GB) 2001-03-08 WO disclosed