Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.63 |
| ▸ | ESRRA | P11474 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245325 | 0.90 | PPARG (0.70) | PPARGESRRAFFAR1PPARA | |
| SCHEMBL3243676 | 0.88 | PPARG (0.69) | PPARGESRRAFFAR1PPARA | |
| SCHEMBL3246551 | 0.88 | PPARG (0.65) | PPARGESRRAFFAR1PPARA | |
| SCHEMBL3247410 | 0.87 | PPARG (0.61) | PPARGESRRAFFAR1PPARA | |
| SCHEMBL7494478 | 0.86 | PPARG (0.62) | PPARGESRRAFFAR1PPARA | |
| SCHEMBL3243649 | 0.85 | PPARG (0.69) | PPARGESRRAFFAR1PPARA | |
| SCHEMBL3237350 | 0.85 | PPARG (0.73) | PPARGESRRAFFAR1PPARA | |
| SCHEMBL3237879 | 0.84 | PPARG (0.64) | PPARGESRRAFFAR1PPARA | |
| SCHEMBL3238312 | 0.83 | PPARG (0.62) | PPARGESRRAFFAR1PPARA | |
| SCHEMBL3244741 | 0.83 | PPARG (0.70) | PPARGESRRAFFAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | claimed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |