Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.36 |
| ▸ | NAMPT | P43490 | 4/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397648 | 0.86 | F10 (0.41) | NAMPTCYP2C9NR1H2CCNKCDK12 | |
| SCHEMBL1652849 | 0.82 | F10 (0.36) | NAMPTCYP2C9NR1H2CDK4CDK6 | |
| SCHEMBL4385719 | 0.81 | F10 (0.35) | NAMPTNR1H2 | |
| SCHEMBL27526708 | 0.81 | F10 (0.36) | NAMPTCYP2C9NR1H2CCNKCDK12 | |
| SCHEMBL27572872 | 0.81 | SCN9A (0.38) | SCN9ANAMPTPDCD1CD274KMT2A | |
| SCHEMBL27572855 | 0.79 | F10 (0.36) | NAMPTCYP2C9 | |
| SCHEMBL1654543 | 0.79 | F10 (0.39) | NAMPTCYP2C9NR1H2 | |
| SCHEMBL18848182 | 0.78 | NR1H2 (0.40) | NAMPTCYP2C9NR1H2 | |
| Tert-Butyl Formate SCHEMBL27572856 | 0.77 | F10 (0.42) | NAMPTCYP2C9CCNKCDK12 | |
| SCHEMBL27108521 | 0.77 | NR1H2 (0.46) | NAMPTCYP2C9NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | disclosed |