Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7506014 | 0.90 | SPHK1 (0.43) | SPHK1HSD11B2BRD4HCRTR2TSHR | |
| SCHEMBL7503893 | 0.90 | SPHK1 (0.43) | SPHK1HSD11B2BRD4HCRTR2TSHR | |
| SCHEMBL1863729 | 0.87 | SPHK1 (0.46) | SPHK1HSD11B2BRD4HCRTR2TSHR | |
| SCHEMBL14489664 | 0.87 | SPHK1 (0.46) | SPHK1HSD11B2BRD4HCRTR2TSHR | |
| SCHEMBL1863728 | 0.87 | SPHK1 (0.46) | SPHK1HSD11B2BRD4HCRTR2TSHR | |
| SCHEMBL2082395 | 0.86 | SPHK1 (0.51) | SPHK1HSD11B2BRD4HCRTR2SMN1; SMN2 | |
| SCHEMBL2082390 | 0.86 | SPHK1 (0.51) | SPHK1HSD11B2BRD4HCRTR2SMN1; SMN2 | |
| SCHEMBL2326706 | 0.85 | SPHK1 (0.45) | SPHK1HSD11B2BRD4HCRTR2TSHR | |
| SCHEMBL2326704 | 0.85 | SPHK1 (0.45) | SPHK1HSD11B2BRD4HCRTR2TSHR | |
| SCHEMBL6918603 | 0.85 | SPHK1 (0.45) | SPHK1HSD11B2BRD4HCRTR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | disclosed |