Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18639814 | 1.00 | HPGD (0.37) | HPGDGAACA12CA1CA2 | |
| SCHEMBL4772277 | 0.98 | HPGD (0.37) | HPGDGAACA12CA1CA2 | |
| SCHEMBL560075 | 0.93 | — | — | |
| SCHEMBL4028231 | 0.83 | HPGD (0.38) | HPGDGAACA12CA1CA2 | |
| SCHEMBL2354161 | 0.82 | — | — | |
| SCHEMBL4598253 | 0.79 | EPHX1 (0.37) | HPGDGAACA12CA1CA2 | |
| SCHEMBL5329524 | 0.79 | HPGD (0.36) | HPGDGAACA12CA1CA2 | |
| SCHEMBL10808899 | 0.79 | CHRM2 (0.46) | HPGDGAACHRM2CHRM4CHRM5 | |
| SCHEMBL5329527 | 0.76 | KMT2A (0.37) | GAACA12CA1CA2CA9 | |
| SCHEMBL3109587 | 0.74 | GAA (0.36) | HPGDGAACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
| US-8470772-B2 | Leptin agonist and methods of use | Temple University—Of the Commonwealth System of Higher Education (US) | 2013-06-25 | — | — | US | claimed |
| US-20110015124-A1 | LEPTIN AGONIST AND METHODS OF USE | Temple University of the Commomwealth System of Higher Eduacation (US) | 2011-01-20 | — | — | US | claimed |
| EP-2252314-A2 | LEPTIN AGONIST AND METHODS OF USE | Temple University - Of The Commonwealth System of Higher Education (US) | 2010-11-24 | — | — | EP | claimed |
| WO-2009108340-A2 | LEPTIN AGONIST AND METHODS OF USE | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2009-09-03 | — | — | WO | claimed |
| JP-3912798-B2 | — | — | 2007-05-09 | — | — | JP | claimed |
| EP-0871653-B1 | NOVEL AMINO ACID DERIVATIVES, METHODS OF PRODUCING THEM, AND PHARMACEUTICAL COMPOUNDS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-03-26 | — | — | EP | claimed |
| EP-0979827-A1 | Peptides having tachykinin antagonist activity, a process for preparation thereof and pharmaceutical compositions comprising the same | Boehringer Ingelheim Pharma KG (DE) | 2000-02-16 | — | — | EP | claimed |
| JP-2000501382-A | — | — | 2000-02-08 | — | — | JP | claimed |
| EP-0610487-B1 | NEW AMINOACID DERIVATES, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-10 | — | — | EP | claimed |
| EP-0804463-A1 | NEUROKININE (TACHYKININE) ANTAGONISTS | BOEHRINGER INGELHEIM KG (DE) | 1997-11-05 | — | — | EP | claimed |
| EP-0802922-A1 | NOVEL AMINO ACID DERIVATIVES, METHOD OF PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM KG (DE) | 1997-10-29 | — | — | EP | claimed |
| WO-1997017362-A1 | NOVEL AMINO ACID DERIVATIVES, METHODS OF PRODUCING THEM, AND PHARMACEUTICAL COMPOUNDS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM KG (DE) | 1997-05-15 | — | — | WO | claimed |
| WO-1995030687-A1 | NEUROKININE (TACHYKININE) ANTAGONISTS | BOEHRINGER INGELHEIM KG (DE) | 1995-11-16 | — | — | WO | claimed |
| WO-1995023810-A1 | NOVEL AMINO ACID DERIVATIVES, METHOD OF PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM KG (DE) | 1995-09-08 | — | — | WO | claimed |
| EP-0394989-B1 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-12-21 | — | — | EP | claimed |
| EP-0610487-A1 | NEW AMINOACID DERIVATES, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM KG (DE) | 1994-08-17 | — | — | EP | claimed |
| WO-1994005693-A1 | NEW AMINOACID DERIVATES, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM KG (DE) | 1994-03-17 | — | — | WO | claimed |
| US-5164372-A | Treatment of respiratory disorders, inflammation, dermatitis | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-11-17 | — | — | US | claimed |
| EP-0394989-A2 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | HPGD 2910/4885GAA 2187/4885CA12 3378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.