Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 4/20 | 0.37 |
| ▸ | PFKFB2 | O60825 | 3/20 | 0.37 |
| ▸ | PFKFB1 | P16118 | 3/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.37 |
| ▸ | FAP | Q12884 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496749 | 1.00 | DPP4 (0.41) | DPP4HRH3PFKFB3PFKFB2PFKFB1 | |
| SCHEMBL7482926 | 0.93 | DPP4 (0.41) | DPP4HRH3PFKFB3PFKFB2PFKFB1 | |
| SCHEMBL7482932 | 0.93 | DPP4 (0.41) | DPP4HRH3PFKFB3PFKFB2PFKFB1 | |
| SCHEMBL7494337 | 0.93 | DPP4 (0.41) | DPP4HRH3PFKFB3PFKFB2PFKFB1 | |
| SCHEMBL7441287 | 0.91 | SLC6A4 (0.40) | DPP4HRH3PFKFB3PFKFB2PFKFB1 | |
| SCHEMBL7496050 | 0.91 | SLC6A4 (0.40) | DPP4HRH3PFKFB3PFKFB2PFKFB1 | |
| SCHEMBL7452025 | 0.91 | DPP4 (0.39) | DPP4HRH3PFKFB3PFKFB2PFKFB1 | |
| SCHEMBL7452013 | 0.91 | DPP4 (0.39) | DPP4HRH3PFKFB3PFKFB2PFKFB1 | |
| SCHEMBL7452017 | 0.91 | DPP4 (0.39) | DPP4HRH3PFKFB3PFKFB2PFKFB1 | |
| SCHEMBL7487691 | 0.90 | DPP4 (0.43) | DPP4HRH3DPP8FAPDPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |