SCHEMBL7498596

SCHEMBL7498596

N#Cc1cccc(NC(=O)Nc2cc3c(cc2CCN2CCC(Cc4ccccc4)CC2)OCO3)c1

nearest known ligand 0.85

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 20/20 0.85
HTR2A P28223 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL7493891 0.99 CCR3 (0.83) CCR3HTR2A
SCHEMBL6703876 0.92 CCR3 (1.00) CCR3HTR2A
SCHEMBL7500974 0.87 CCR3 (0.84) CCR3HTR2A
Hydrochloric Acid SCHEMBL7500878 0.86 CCR3 (0.83) CCR3HTR2A
SCHEMBL7498604 0.83 CCR3 (0.73) CCR3HTR2A
Iodide SCHEMBL6701651 0.81 CCR3 (1.00) CCR3HTR2A
SCHEMBL6704383 0.81 CCR3 (1.00) CCR3HTR2A
SCHEMBL6701753 0.81 CCR3 (1.00) CCR3HTR2A
SCHEMBL6215640 0.79 CCR3 (1.00) CCR3HTR2A
SCHEMBL6703024 0.79 CCR3 (1.00) CCR3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140087-A4 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY DU PONT PHARM CO (US) 2002-04-03 EP claimed
EP-1140087-A1 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY Du Pont Pharmaceuticals Company (US) 2001-10-10 EP claimed
WO-2000035454-A1 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY DU PONT PHARMACEUTICALS COMPANY (US) 2000-06-22 WO claimed