SCHEMBL7499130

SCHEMBL7499130

CS(=O)(=O)OC[C@H]1CN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CC(=O)N1Cc1ccc2c(N)ncnc2c1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7499139 1.00 F10 (0.79) F10
SCHEMBL1385565 0.94 F10 (0.80) F10
SCHEMBL1385563 0.94 F10 (0.80) F10
SCHEMBL4392959 0.94 F10 (0.80) F10
SCHEMBL1384671 0.91 F10 (0.77) F10
SCHEMBL1384676 0.91 F10 (0.77) F10
SCHEMBL1386479 0.91 F10 (0.77) F10
SCHEMBL1652928 0.89 F10 (0.89) F10
SCHEMBL4395249 0.89 F10 (0.80) F10
SCHEMBL1386592 0.89 F10 (0.80) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1208097-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS Aventis Pharmaceuticals Inc. (US) 2002-05-29 EP disclosed
WO-2001007436-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS AVENTIS PHARMACEUTICALS INC. (US) 2001-02-01 WO disclosed