Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496369 | 0.96 | TACR2 (0.47) | TACR2KCNH2 | |
| SCHEMBL7493778 | 0.95 | KCNH2 (0.52) | TACR2KCNH2 | |
| SCHEMBL7499164 | 0.93 | TACR2 (0.49) | TACR2 | |
| SCHEMBL7503867 | 0.92 | TACR2 (0.60) | TACR2 | |
| SCHEMBL7502368 | 0.92 | TACR2 (0.46) | TACR2KCNH2 | |
| SCHEMBL7494561 | 0.91 | KCNH2 (0.44) | TACR2KCNH2 | |
| SCHEMBL7497142 | 0.91 | TACR2 (0.50) | TACR2KCNH2 | |
| SCHEMBL7497636 | 0.90 | TACR2 (0.48) | TACR2KCNH2 | |
| SCHEMBL7491406 | 0.90 | TACR2 (0.49) | TACR2KCNH2 | |
| SCHEMBL7492977 | 0.89 | TACR2 (0.48) | TACR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888336-B1 | NOVEL SUBSTITUTED N-METHYL-N-(4-(4-(1H-BENZIMIDAZOL-2-YL-AMINO)P IPERIDIN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | AVENTIS PHARMA INC (US) | 2002-08-07 | — | — | EP | disclosed |
| US-5922737-A | Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases | HOECHST MARION ROUSSEL, INC. (US) | 1999-07-13 | — | — | US | disclosed |