Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 15/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.55 |
| ▸ | CCR3 | P51677 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757825 | 0.80 | SLC6A2 (0.54) | SLC6A2SLC6A3 | |
| SCHEMBL6331510 | 0.80 | CCR3 (0.81) | EPHX2EPHX1CCR3SLC6A2SLC6A3 | |
| SCHEMBL5758650 | 0.79 | CCR3 (0.60) | EPHX2CCR3SLC6A2SLC6A3 | |
| SCHEMBL6337374 | 0.79 | CCR3 (0.77) | EPHX2EPHX1CCR3MAPK1SLC6A2 | |
| SCHEMBL7497930 | 0.78 | CCR3 (0.61) | CCR3 | |
| SCHEMBL6338952 | 0.77 | EPHX2 (0.55) | EPHX2EPHX1CCR3MAPK1SLC6A2 | |
| SCHEMBL6407882 | 0.75 | CCR3 (0.65) | EPHX2EPHX1CCR3MAPK1 | |
| SCHEMBL5757908 | 0.74 | CARM1 (0.59) | SLC6A2SLC6A3 | |
| SCHEMBL7498516 | 0.74 | CCR3 (0.58) | EPHX2EPHX1CCR3MAPK1 | |
| SCHEMBL5755428 | 0.74 | SLC6A2 (0.47) | CCR3SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140086-A4 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARM CO (US) | 2002-04-03 | — | — | EP | claimed |
| EP-1140086-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000035451-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | claimed |
| EP-1140086-A4 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARM CO (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1140086-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035451-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |