Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL3689465 | 1.00 | — | — | |
| Glycine SCHEMBL28116895 | 0.96 | GLRA1 (0.77) | — | |
| Glycine SCHEMBL4357419 | 0.96 | — | — | |
| Glycine SCHEMBL5907901 | 0.96 | — | — | |
| Glycine SCHEMBL8201410 | 0.96 | — | — | |
| Glycine SCHEMBL30898297 | 0.96 | — | — | |
| Glycine SCHEMBL4850247 | 0.92 | — | — | |
| Glycine SCHEMBL2163124 | 0.92 | — | — | |
| Glycine SCHEMBL3941231 | 0.92 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL3145399 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112858271-A | Water ammonia nitrogen detection reagent, detection system and detection method | 杭州陆恒生物科技有限公司 | 2021-05-28 | — | — | CN | disclosed |
| EP-1007722-A4 | COLD-ACTIVE PROTEASE CP-58 AND PSYCHROTROPHIC BACTERIA | PROCTER & GAMBLE (US) | 2002-12-04 | — | — | EP | disclosed |
| EP-1007722-A1 | COLD-ACTIVE PROTEASE CP-58 AND PSYCHROTROPHIC BACTERIA | THE PROCTER & GAMBLE COMPANY (US) | 2000-06-14 | — | — | EP | disclosed |
| WO-1997030172-A1 | COLD-ACTIVE PROTEASE CP-58 AND PSYCHROTROPHIC BACTERIA | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-21 | — | — | WO | disclosed |