SCHEMBL7500346

SCHEMBL7500346

Cc1c(CN)sc2cncn12

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 20/20 0.40
TDO2 P48775 20/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7495796 0.75 IDO1 (0.43) IDO1TDO2
SCHEMBL7498851 0.70 IDO1 (0.41) IDO1TDO2
SCHEMBL7494223 0.70 IDO1 (0.33) IDO1TDO2
SCHEMBL20743428 0.66 IDO1 (0.48) IDO1TDO2
SCHEMBL7496305 0.66 IDO1 (0.41) IDO1TDO2
SCHEMBL7490921 0.64 IDO1 (0.47) IDO1TDO2
SCHEMBL5045139 0.64 IDO1 (0.37) IDO1TDO2
SCHEMBL22188406 0.64 IDO1 (0.46) IDO1TDO2
SCHEMBL20743838 0.64 IDO1 (0.46) IDO1TDO2
SCHEMBL20743902 0.64 IDO1 (0.48) IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0760370-B1 NOVEL CARBAPENEM DERIVATIVES MEIJI SEIKA CO (JP) 2002-08-07 EP disclosed
US-5990101-A Carbapenem derivatives MEIJI SEIKA KABUSHIKI KAISHA (JP) 1999-11-23 US disclosed
EP-0760370-A1 NOVEL CARBAPENEM DERIVATIVES MEIJI SEIKA KABUSHIKI KAISHA (JP) 1997-03-05 EP disclosed