SCHEMBL7500478

SCHEMBL7500478

CCCN(CCC)C(=O)C1CCCN1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRCP P42785 2/20 0.46
SCN4A P35499 1/20 0.44
DPP7 Q9UHL4 1/20 0.41
GLI1 P08151 1/20 0.40
BCHE P06276 1/20 0.38
NOS2 P35228 2/20 0.37
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
TLR2 O60603 1/20 0.36
DPP4 P27487 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10827185 0.90 PRCP (0.51) PRCPSCN4ADPP7GLI1BCHE
Hydrochloric Acid SCHEMBL9439145 0.87 PRCP (0.52) PRCPSCN4ADPP7GLI1BCHE
SCHEMBL3632516 0.85 SCN4A (0.46) PRCPSCN4ADPP7GLI1NOS2
SCHEMBL5048080 0.85 SCN4A (0.46) PRCPSCN4ADPP7GLI1NOS2
Hydrochloric Acid SCHEMBL1190797 0.84 SCN4A (0.45) PRCPSCN4ADPP7GLI1NOS2
SCHEMBL26477623 0.84 SCN4A (0.42) PRCPSCN4ADPP7GLI1NOS2
SCHEMBL26370260 0.84 SCN4A (0.42) PRCPSCN4ADPP7GLI1NOS2
Hydrochloric Acid SCHEMBL15847061 0.84 SCN4A (0.45) PRCPSCN4ADPP7GLI1NOS2
SCHEMBL9279932 0.82 MEN1 (0.52) SCN4A
Hydrochloric Acid SCHEMBL9287532 0.81 MEN1 (0.51) SCN4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110546136-B Proline-based neuropeptide FF receptor modulators 研究三角协会 2023-07-18 CN disclosed
CN-110546136-A proline-based neuropeptide FF receptor modulators RES TRIANGLE INST 2019-12-06 CN disclosed
EP-0826673-B1 ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME DAINIPPON PHARMACEUTICAL CO (JP) 2002-11-20 EP disclosed
US-5972946-A NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1999-10-26 US disclosed
EP-0826673-A1 ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1998-03-04 EP disclosed