Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 3/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3991382 | 0.88 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL29997797 | 0.80 | KLK7 (0.51) | NR1H2NR1H3KLK7PSEN1PSEN2 | |
| SCHEMBL25697955 | 0.77 | NR1H2 (0.47) | NR1H2NR1H3KLK7STSGPR119 | |
| SCHEMBL29997742 | 0.77 | NR1H2 (0.47) | NR1H2NR1H3KLK7STSGPR119 | |
| SCHEMBL29997519 | 0.76 | KLK7 (0.46) | NR1H2NR1H3KLK7STSGPR119 | |
| SCHEMBL14417557 | 0.76 | NR1H2 (0.46) | NR1H2NR1H3KLK7STSGPR119 | |
| SCHEMBL29997998 | 0.76 | NR1H2 (0.46) | NR1H2NR1H3KLK7STSGPR119 | |
| SCHEMBL29997912 | 0.76 | NR1H2 (0.46) | NR1H2NR1H3KLK7STSGPR119 | |
| SCHEMBL582271 | 0.75 | NR1H2 (0.53) | NR1H2NR1H3KLK7STSPARP1 | |
| SCHEMBL15353299 | 0.75 | NR1H2 (0.53) | NR1H2NR1H3KLK7STSPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869968-A1 | GROWTH-HORMONE SECRETAGOGUES | PFIZER INC. (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024369-A1 | GROWTH-HORMONE SECRETAGOGUES | PFIZER INC. (US) | 1997-07-10 | — | — | WO | disclosed |