Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 19/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706317 | 0.86 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL203894 | 0.86 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL752120 | 0.85 | HCRTR1 (0.45) | HCRTR1HCRTR2USP30 | |
| SCHEMBL17644204 | 0.85 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL1293347 | 0.83 | HCRTR1 (0.64) | HCRTR1HCRTR2 | |
| SCHEMBL19385344 | 0.81 | USP30 (0.66) | HCRTR1HCRTR2USP30 | |
| SCHEMBL19385343 | 0.81 | USP30 (0.66) | HCRTR1HCRTR2USP30 | |
| SCHEMBL13494179 | 0.80 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL2512532 | 0.80 | HTR2B (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL934057 | 0.80 | CYP3A4 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |