Aniline

Aniline

SCHEMBL7501280

CN(C)C.Nc1ccccc1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.73
CYP3A4 P08684 5/20 0.50
MAPT P10636 5/20 0.50
ALDH1A1 P00352 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CYP2D6 P10635 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TP53 P04637 1/20 0.48
ALOX15 P16050 1/20 0.48
MAPK1 P28482 1/20 0.48
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MAOA P21397 5/20 0.43
MAOB P27338 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL5053979 0.97 TSHR (0.69) TSHRCYP3A4MAPTALDH1A1TDP1
Aniline SCHEMBL27447053 0.97 TSHR (0.69) TSHRCYP3A4MAPTALDH1A1TDP1
Aniline SCHEMBL11121974 0.97 TSHR (0.69) TSHRCYP3A4MAPTALDH1A1TDP1
Aniline SCHEMBL27556752 0.97 TSHR (0.69) TSHRCYP3A4MAPTALDH1A1TDP1
Aniline SCHEMBL7406312 0.90 TSHR (0.69) TSHRCYP3A4MAPTALDH1A1TDP1
Aniline SCHEMBL27674596 0.89
Aniline SCHEMBL1984004 0.86
Aniline SCHEMBL11818606 0.86
Aniline SCHEMBL9755597 0.86 TSHR (1.00) TSHRCYP3A4MAPTALDH1A1TDP1
SCHEMBL18517570 0.86 TSHR (1.00) TSHRCYP3A4MAPTALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104144951-A PROCESS FOR PURGING PROPANE IN A POLYPROPYLENE MANUFACTURING PROCESS TOTAL PETROCHEMICALS RES FELUY 2014-11-12 CN disclosed
CN-103275303-A Method for synthetizing hydrogenated bisphenol A epoxy resin under catalysis of ammonium salt NANJING UNIVERSITY OF TECHNOLOGY 2013-09-04 CN disclosed
EP-1189692-A1 NOVEL TRIAZINE-BASED DETOXIFICATION AGENTS AND THEIR USE Prometic Biosciences Ltd (GB) 2002-03-27 EP disclosed
WO-2000067900-A1 NOVEL TRIAZINE-BASED DETOXIFICATION AGENTS AND THEIR USE PROMETIC BIOSCIENCES LTD. (GB) 2000-11-16 WO disclosed