Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.58 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.46 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.46 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | GLI1 | P08151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501986 | 0.96 | SCN4A (0.53) | SCN4APFKFB2PFKFB1PFKFB3PDK2 | |
| SCHEMBL26364558 | 0.85 | SCN4A (0.58) | SCN4APFKFB2PFKFB1PFKFB3MLNR | |
| SCHEMBL29517131 | 0.85 | SCN4A (0.58) | SCN4APFKFB2PFKFB1PFKFB3MLNR | |
| SCHEMBL13723611 | 0.85 | SCN4A (0.58) | SCN4APFKFB2PFKFB1PFKFB3SLC6A3 | |
| SCHEMBL26364702 | 0.85 | SCN4A (0.58) | SCN4APFKFB2PFKFB1PFKFB3MLNR | |
| SCHEMBL18580371 | 0.85 | SCN4A (0.65) | SCN4APFKFB2PFKFB1PFKFB3SLC6A2 | |
| SCHEMBL30715013 | 0.84 | SCN4A (0.57) | SCN4APFKFB2PFKFB1PFKFB3HTR2C | |
| SCHEMBL15650741 | 0.81 | SCN4A (0.53) | SCN4APFKFB2PFKFB1PFKFB3SLC6A2 | |
| SCHEMBL26364480 | 0.81 | SCN4A (0.53) | SCN4APFKFB2PFKFB1PFKFB3MLNR | |
| SCHEMBL27634766 | 0.81 | SCN4A (0.53) | SCN4APFKFB2PFKFB1PFKFB3SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826673-B1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0826673-A1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |