Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 18/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7506383 | 0.90 | P2RY2 (0.51) | P2RY2 | |
| SCHEMBL7840113 | 0.87 | P2RY2 (0.82) | P2RY2HTT | |
| SCHEMBL7840419 | 0.86 | P2RY2 (0.76) | P2RY2HTT | |
| SCHEMBL7506087 | 0.85 | P2RY2 (0.51) | P2RY2 | |
| SCHEMBL7841848 | 0.83 | P2RY2 (0.73) | P2RY2POLB | |
| SCHEMBL7841445 | 0.83 | P2RY2 (0.76) | P2RY2 | |
| SCHEMBL7507177 | 0.82 | P2RY2 (0.63) | P2RY2POLB | |
| SCHEMBL7839452 | 0.81 | P2RY2 (0.72) | P2RY2HTTPOLB | |
| SCHEMBL7843516 | 0.80 | P2RY2 (0.71) | P2RY2 | |
| SCHEMBL7839451 | 0.79 | P2RY2 (0.70) | P2RY2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042320-B1 | NEW COMPOUNDS WHICH ARE P2-PURINOCEPTOR 7-TRANSMEMBRANE (TM) G-PROTEIN COUPLED RECEPTOR ANTAGONISTS | ASTRAZENECA UK LTD (GB) | 2002-02-13 | — | — | EP | claimed |
| US-6218376-B1 | FOR TREATING INFLAMMATORY DISEASES | ASTRAZENECA UK LIMITED (GB) | 2001-04-17 | — | — | US | claimed |
| EP-1042320-B1 | NEW COMPOUNDS WHICH ARE P2-PURINOCEPTOR 7-TRANSMEMBRANE (TM) G-PROTEIN COUPLED RECEPTOR ANTAGONISTS | ASTRAZENECA UK LTD (GB) | 2002-02-13 | — | — | EP | disclosed |
| US-6218376-B1 | FOR TREATING INFLAMMATORY DISEASES | ASTRAZENECA UK LIMITED (GB) | 2001-04-17 | — | — | US | disclosed |