Phosphine

Phosphine

SCHEMBL7506

BrOBr.P

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL28143520 0.91
SCHEMBL180757 0.89
SCHEMBL14151417 0.80
SCHEMBL11659799 0.80
SCHEMBL15788977 0.80
SCHEMBL5897645 0.80
SCHEMBL15366348 0.80
SCHEMBL4301414 0.80
SCHEMBL7056855 0.80
SCHEMBL7615128 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070932-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF ANNEXON INC (US) 2026-03-12 US disclosed
EP-4673451-A1 POLYMERIZABLE MONOMER Universität Linz (AT) 2026-01-07 EP disclosed
US-12478616-B2 PI3K inhibitors and uses thereof SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2025-11-25 US disclosed
US-12466822-B2 Heterocyclic compounds as immunomodulators INCYTE CORPORATION (US) 2025-11-11 US disclosed
US-20250163048-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. 2025-05-22 US disclosed
CN-115989224-B Plasma kallikrein inhibitors 默沙东有限责任公司 2025-02-25 CN disclosed
CN-119255997-A Modulators of c-MYC mRNA translation and their use in the treatment of cancer 艾尼莫生物科技公司 2025-01-03 CN disclosed
CN-119233976-A Modulators of c-MYC mRNA translation and their use in the treatment of cancer 艾尼莫生物科技公司 2024-12-31 CN disclosed
EP-4469455-A1 COMPOUNDS AND METHODS OF USE Tango Therapeutics, Inc. (US) 2024-12-04 EP disclosed
WO-2024178449-A1 POLYMERIZABLE MONOMER Universität Linz (AT) 2024-09-06 WO disclosed
EP-1644336-A1 NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND THEIR USE IN INCREASING ENDOGENEOUS ERYTHROPOIETIN FIBROGEN, INC. (US) 2006-04-12 EP disclosed
EP-1611109-A1 NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF TAISHO PHARMACEUTICAL CO., LTD (JP) 2006-01-04 EP disclosed
WO-2004108681-A1 NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND THEIR USE IN INCREASING ENDOGENOUS ERYTHROPOIETIN FIBROGEN, INC. (US) 2004-12-16 WO disclosed
WO-2004087680-A1 NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF TAISHO PHARMACEUTICAL CO., LTD. (JP) 2004-10-14 WO disclosed
US-4886790-A CHEMOTPHERAPY THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1989-12-12 US disclosed
EP-0251724-A2 Compositions containing bisphenol compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-01-07 EP disclosed
EP-0227528-A1 Process for preparing halogenated trialkyl phosphate esters THE DOW CHEMICAL COMPANY (US) 1987-07-01 EP disclosed
US-4544501-A ANTINEOPLASTIC THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1985-10-01 US disclosed
US-4177200-A Silyl phosphates as neutralizing agents for alkali metal hydroxides GENERAL ELECTRIC COMPANY (US) 1979-12-04 US disclosed
US-4125551-A FROM A POLYSILOXANE AND PHOSPHORIC ACID GENERAL ELECTRIC COMPANY (US) 1978-11-14 US disclosed