Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 1.00 |
| ▸ | PTPRF | P10586 | 1/20 | 0.69 |
| ▸ | PTPRA | P18433 | 1/20 | 0.69 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.69 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505812 | 0.86 | PTPN1 (0.76) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7506554 | 0.85 | PTPN1 (1.00) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7506695 | 0.85 | PTPN1 (0.75) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7498026 | 0.82 | PTPN1 (1.00) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7502934 | 0.82 | PTPN1 (1.00) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4261645 | 0.82 | PTPN1 (1.00) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7499043 | 0.81 | PTPN1 (1.00) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4267832 | 0.81 | PTPN1 (0.68) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4267828 | 0.81 | PTPN1 (0.68) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7505309 | 0.80 | PTPN1 (0.66) | PTPN1PTPRFPTPRAPTPN7DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077967-B1 | BIPHENYL OXO-ACETIC ACIDS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | WYETH CORP (US) | 2002-12-04 | — | — | EP | claimed |