Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 19/20 | 0.66 |
| ▸ | MKNK1 | Q9BUB5 | 14/20 | 0.66 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505890 | 0.88 | MKNK2 (0.57) | MKNK2MKNK1LCK | |
| SCHEMBL7505439 | 0.86 | MKNK2 (0.66) | MKNK2MKNK1LCK | |
| SCHEMBL7509435 | 0.85 | MKNK2 (0.52) | MKNK2MKNK1LCK | |
| SCHEMBL7025681 | 0.82 | MKNK1 (0.87) | MKNK2MKNK1LCK | |
| SCHEMBL7499230 | 0.81 | MKNK2 (0.59) | MKNK2MKNK1LCK | |
| SCHEMBL7508884 | 0.79 | MKNK2 (0.58) | MKNK2MKNK1LCK | |
| SCHEMBL18803625 | 0.79 | MKNK2 (1.00) | MKNK2MKNK1 | |
| SCHEMBL18803652 | 0.78 | MKNK2 (1.00) | MKNK2MKNK1 | |
| SCHEMBL7024590 | 0.77 | APP (0.54) | — | |
| SCHEMBL7497343 | 0.77 | MKNK1 (0.60) | MKNK2MKNK1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206265-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-1206265-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001000213-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |