Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 6/20 | 0.41 |
| ▸ | F7 | P08709 | 2/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | F9 | P00740 | 2/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407103 | 0.90 | SMN1; SMN2 (0.46) | F2F10F7KDM4EALDH1A1 | |
| SCHEMBL7405075 | 0.86 | F2 (0.44) | F2F10F7ALDH1A1 | |
| SCHEMBL7510086 | 0.85 | F10 (0.45) | F2F10F7ALDH1A1F9 | |
| SCHEMBL7408796 | 0.84 | F2 (0.44) | F2F10F7CYP3A4CYP1A2 | |
| SCHEMBL7406764 | 0.80 | F2 (0.37) | F2F10F7ALDH1A1F9 | |
| SCHEMBL7403772 | 0.78 | F10 (0.47) | F2F10F7ALDH1A1F9 | |
| SCHEMBL7405163 | 0.78 | F2 (0.53) | F2F10F7KLK1KLK5 | |
| SCHEMBL7405066 | 0.77 | F2 (0.48) | F2F10F7F9KLK1 | |
| SCHEMBL7397941 | 0.75 | F7 (0.50) | F2F10F7ALDH1A1KLK1 | |
| SCHEMBL7401825 | 0.75 | F10 (0.49) | F2NPY5RF10F7KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |