Sugi Predict

Sugi Predict / Compounds / SCHEMBL7510322

SCHEMBL7510322

SCHEMBL7510322

Cc1cc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)cc(C)c1O[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 19/20 1.00
▸ PTPRF P10586 1/20 0.75
▸ PTPRA P18433 1/20 0.75
▸ PTPN7 P35236 1/20 0.75
▸ DUSP3 P51452 1/20 0.75
▸ PPARG P37231 1/20 0.64
▸ PPARA Q07869 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7499865 0.89 PTPN1 (1.00) PTPN1PTPRFPTPRAPTPN7DUSP3
SCHEMBL7498026 0.86 PTPN1 (1.00) PTPN1PTPRFPTPRAPTPN7DUSP3
SCHEMBL7502934 0.86 PTPN1 (1.00) PTPN1PTPRFPTPRAPTPN7DUSP3
SCHEMBL4261645 0.86 PTPN1 (1.00) PTPN1PTPRFPTPRAPTPN7DUSP3
SCHEMBL7498480 0.82 PTPN1 (1.00) PTPN1PTPRFPTPRAPTPN7DUSP3
SCHEMBL7506554 0.82 PTPN1 (1.00) PTPN1PTPRFPTPRAPTPN7DUSP3
SCHEMBL7496701 0.80 PTPN1 (1.00) PTPN1PTPRFPTPRAPTPN7DUSP3
SCHEMBL4271340 0.80 PTPN1 (0.67) PTPN1PTPRFPTPRAPTPN7DUSP3
SCHEMBL7499043 0.79 PTPN1 (1.00) PTPN1PTPRFPTPRAPTPN7DUSP3
Tromethamine SCHEMBL7501623 0.79 PTPN1 (0.85) PTPN1PTPRFPTPRAPTPN7DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1077967-B1 BIPHENYL OXO-ACETIC ACIDS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA WYETH CORP (US) 2002-12-04 — — EP claimed