Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 4/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502046 | 0.91 | ADORA2A (0.44) | KDM4EADORA2AADORA1ARMEN1 | |
| SCHEMBL7506592 | 0.89 | ADORA2A (0.43) | KDM4EADORA2AADORA1ARHCAR2 | |
| SCHEMBL7509764 | 0.89 | ADORA2A (0.41) | KDM4EADORA2AADORA1ARHCAR2 | |
| SCHEMBL7503352 | 0.88 | ADORA2A (0.45) | ADORA2AADORA1ARHCAR2TAAR1 | |
| SCHEMBL7508341 | 0.87 | ADORA2A (0.40) | KDM4EADORA2AADORA1AR | |
| SCHEMBL7506949 | 0.87 | ADORA2A (0.40) | KDM4EADORA2AADORA1ARRAB9A | |
| SCHEMBL7505151 | 0.87 | CYP11B1 (0.45) | KDM4EADORA2AADORA1ARKMT2A | |
| SCHEMBL7509565 | 0.87 | AR (0.43) | KDM4EADORA2AADORA1AR | |
| SCHEMBL7512607 | 0.86 | ADORA2A (0.41) | KDM4EADORA2AADORA1ARMEN1 | |
| SCHEMBL7505635 | 0.84 | AR (0.47) | KDM4EADORA2AADORA1ARHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |
| US-5294622-A | Fungicides, insecticides, miticides | DOWELANCO (US) | 1994-03-15 | — | — | US | disclosed |
| US-5114939-A | Amine or ether substitutes compounds of quinoline or cinnoline | DOWELANCO (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0326331-A2 | Substituted quinolines and cinnolines | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |