Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 8/20 | 0.74 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.50 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885741 | 0.91 | ERN1 (0.57) | ERN1CA1CA2L3MBTL1MAPT | |
| SCHEMBL31145561 | 0.86 | ERN1 (1.00) | ERN1GPR35L3MBTL1MAPTKMT2A | |
| SCHEMBL311131 | 0.86 | ERN1 (1.00) | ERN1GPR35L3MBTL1MAPTKMT2A | |
| SCHEMBL30661191 | 0.85 | ERN1 (0.96) | ERN1GPR35L3MBTL1MAPTKMT2A | |
| Potassium SCHEMBL30661194 | 0.85 | ERN1 (0.96) | ERN1GPR35L3MBTL1MAPTKMT2A | |
| SCHEMBL29114874 | 0.85 | ERN1 (0.96) | ERN1GPR35L3MBTL1MAPTKMT2A | |
| SCHEMBL11417397 | 0.85 | ERN1 (0.96) | ERN1GPR35L3MBTL1MAPTKMT2A | |
| SCHEMBL29114884 | 0.85 | ERN1 (0.96) | ERN1GPR35L3MBTL1MAPTKMT2A | |
| SCHEMBL11417400 | 0.85 | ERN1 (0.96) | ERN1GPR35L3MBTL1MAPTKMT2A | |
| SCHEMBL790725 | 0.82 | ERN1 (0.54) | ERN1CA1CA2TLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259491-A1 | 4-IMIDAZOLE DERIVATIVES OF BENZYL AND RESTRICTED BENZYL SULFONAMIDES, SULFAMIDES, UREAS, CARBAMATES AND AMIDES AND THEIR USE AS ALPHA-1A AGONISTS | Abbott Laboratories (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001060802-A1 | 4-IMIDAZOLE DERIVATIVES OF BENZYL AND RESTRICTED BENZYL SULFONAMIDES, SULFAMIDES, UREAS, CARBAMATES, AND AMIDES AND THEIR USE AS ALPHA-1A AGONISTS | ABBOTT LABORATORIES (US) | 2001-08-23 | — | — | WO | disclosed |