Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 15/20 | 0.53 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514177 | 0.93 | P2RY12 (0.47) | P2RY12USP28TLR8TLR7 | |
| SCHEMBL7509882 | 0.87 | P2RY12 (0.70) | P2RY12 | |
| SCHEMBL7509891 | 0.87 | P2RY12 (0.70) | P2RY12 | |
| SCHEMBL7515643 | 0.84 | P2RY12 (0.73) | P2RY12USP28 | |
| SCHEMBL7509278 | 0.83 | P2RY12 (0.53) | P2RY12TLR8TLR7 | |
| SCHEMBL7507158 | 0.83 | P2RY12 (0.72) | P2RY12 | |
| SCHEMBL7509281 | 0.83 | P2RY12 (0.53) | P2RY12TLR8TLR7 | |
| SCHEMBL7507169 | 0.83 | P2RY12 (0.72) | P2RY12 | |
| SCHEMBL7506622 | 0.81 | P2RY12 (0.59) | P2RY12 | |
| SCHEMBL7506625 | 0.81 | P2RY12 (0.59) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0890119-A4 | PHOTOCHROMIC NAPHTHOPYRAN COMPOSITIONS OF NEUTRAL COLOR | TRANSITIONS OPTICAL INC (US) | 2002-07-17 | — | — | EP | disclosed |
| EP-0946561-B1 | TRIAZOLO(4,5-D)PYRIMIDINYL DERIVATIVES AND THEIR USE AS MEDICAMENTS | ASTRAZENECA AB (SE) | 2002-02-13 | — | — | EP | disclosed |
| US-6297232-B1 | TREATMENT OF PLATELET AGGREGATION DISORDERS. | ASTRAZENECA AB (SE) | 2001-10-02 | — | — | US | disclosed |
| EP-0890119-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOSITIONS OF NEUTRAL COLOR | TRANSITIONS OPTICAL, INC. (US) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997037254-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOSITIONS OF NEUTRAL COLOR | TRANSITIONS OPTICAL, INC. (US) | 1997-10-09 | — | — | WO | disclosed |