Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | PRMT3 | O60678 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24930734 | 0.94 | EPHX1 (0.56) | EPHX1SIGMAR1PRMT3NPC1RAB9A | |
| SCHEMBL7776480 | 0.90 | EPHX1 (0.75) | EPHX1SIGMAR1PRMT3NPC1RAB9A | |
| SCHEMBL3420737 | 0.80 | EPHX1 (0.59) | EPHX1SIGMAR1PRMT3NPC1RAB9A | |
| SCHEMBL12196108 | 0.78 | EPHX1 (1.00) | EPHX1HPGDKDM4EALDH1A1 | |
| SCHEMBL14503312 | 0.76 | EPHX1 (0.62) | EPHX1SIGMAR1PRMT3NPC1RAB9A | |
| SCHEMBL2926383 | 0.76 | EPHX1 (0.56) | EPHX1SIGMAR1PRMT3NPC1RAB9A | |
| SCHEMBL8391133 | 0.76 | EPHX1 (0.61) | EPHX1SIGMAR1PRMT3NPC1RAB9A | |
| SCHEMBL6062059 | 0.76 | EPHX1 (0.61) | EPHX1SIGMAR1NPC1RAB9AL3MBTL1 | |
| SCHEMBL8393790 | 0.76 | EPHX1 (0.61) | EPHX1SIGMAR1PRMT3NPC1RAB9A | |
| SCHEMBL10254622 | 0.76 | EPHX1 (0.68) | EPHX1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044194-A4 | RECEPTOR WITH AN AFFINITY FOR COMPOUNDS OF THE OXAZOLINE CLASS | UNIV MELBOURNE (AU) | 2002-01-09 | — | — | EP | disclosed |
| EP-1044194-A1 | RECEPTOR WITH AN AFFINITY FOR COMPOUNDS OF THE OXAZOLINE CLASS | THE UNIVERSITY OF MELBOURNE (AU) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999024411-A1 | RECEPTOR WITH AN AFFINITY FOR COMPOUNDS OF THE OXAZOLINE CLASS | THE UNIVERSITY OF MELBOURNE (AU) | 1999-05-20 | — | — | WO | disclosed |